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A gunman opened fire at a bank building in the US city of Cincinnati yesterday, fatally wounding three people before police shot and killed him, authorities said.

The incident occurred after 9:00 am local time (1300 GMT) at the lobby and loading dock of the 30-story Fifth Third Bank building in the city's downtown business district.

"An individual entered the loading dock area, began firing shots," Cincinnati Police Chief Eliot Isaac said at a news conference.

The gunman then went to the lobby of the building, where police engaged the suspect in a shootout and killed him, the chief said.

"At least three or four of our officers did engage the suspect," Isaac said.